What are the differences between nicotinamide riboside and nicotinamide mononucleotide
What is nicotinamide mononucleotide (NMN)? Nicotinamide mononucleotide (NMN) belongs to the family of B3 vitamins. The molecule is the immediate precursor of NAD + and is involved in the biosynthesis of NAD + in all living things. NMN helps maintain cellular levels of NAD+, thereby facilitating NAD+-dependent cellular activities, such as mitochondrial metabolism, regulation of sirtuins, and PARP activity. Animal studies have demonstrated that NMN administration is effective in increasing NAD+ levels across multiple tissues while improving the outcome of a variety of age-related diseases. Although NMN administration has proven to be safe and to effectively increase NAD+ levels in rodents, the safety and efficacy of NMN supplementation in humans remain unknown. NMN is available in supplement form and is present in various types of food, including broccoli, avocado, and beef. It is also an intermediate compound in the NAD+ salvage pathway, the recycling of nicotinam...